Why do elephants not develop cancerous tumors? .. an issue that cell scientists and cancer oncologists often tried to answer it. within the past, scientists thought that sharks don't develop cancer, but they found that they also develop cancer, which implies that elephants, those larger creatures on the surface of land, stand Alone challenge this most dangerous cellular disease of this era.
"Jin TP53 is that the reason for that miracle." this is often a result published by the Journal of the American Medical Association in mid-August, and a few details were published by the American scientific journal Cell Reports, which makes a speciality of publishing life sciences research, this result came after in-depth research studies dole out by a team My research is at Utah State University, Arizona, USA, and headed by Professor Schiffman, MD, Oncologist at Children's Basic Hospital in Salt Lake City, and Investigator in Cancer Research at HCL.
The elephants were able to break a well known scientific base, achieving a victory for themselves over a disease that threatens human and animal life alike, and opening a door of hope for scientists to beat the dreaded cancer. From this standpoint, the experts hope that the genetic studies of the research team will contribute to Finding a definitive cure for cancer, while everyone understands how long they'll have to cash in of the genetic material of the elephant.
Over the past years, scientists believed that the greater the dimensions of an organism, the upper its incidence of cancer, because animal cells are always in a very state of continuous division, and with each division there's a prospect of a cell mutation that leads to cancerous illnesses, so it's natural for animals to be the biggest, and with the longest life. the foremost susceptible to cancer, but things was different within the case of elephants, which confused cancer scientists, this confusion made them realize that behind this scarcity a mystery must be discovered.
The most important finding of the research study is that elephants have multiple copies of anti-cellular and anti-cellular genes, the primary of which is that the TP53 gene, or what could also be called "tumor suppressor or cancer suppression", which traps cells that contain deformed DNA, and copies over 40 copies Different within the elephant's genome or its genetic material, additionally to the LIF6 gene, which obliterates mutated cells before they will form a tumor, which in step with the evolutionary record wasn't active innumerable years ago, but mysteriously came to life recently.
The most important question here now's, is it possible to learn from this discovery find new treatments for human cancer? The cellular nature of someone doesn't possess only 1 copy of those genetic cells, so can we within the future transfer this remarkable ability to the person to be able to resist cancer?